MINNEAPOLIS — Detroit scored five times in the sixth inning to knock off the first-place Minnesota Twins.

The Twins scored a single run in both the first and second inning, then scored another run in the fifth inning to take a 3-0 lead.

The Tigers then hit Jose Berrios hard in the sixth inning. Berrios continued his struggles by giving up five runs in 5 1/3 innings.

Ronny Rodriguez hit a grand slam in the sixth for the Tigers. Miguel Sano hit two home runs, his 24th and 25th of the season. Jake Cave also hit two home runs.

INDIANS 4, ROYALS 1

CLEVELAND (AP) — Brad Hand bounced back from his recent struggles to record his 30th save, Francisco Lindor hit a two-run homer and Cleveland beat Kansas City.

The All-Star closer, who had blown three consecutive saves, gave up a leadoff single to Alex Gordon in the ninth. Pinch-hitter Cheslor Cuthbert bounced into a double play, extending his hitless streak to 0 for 39, and Bubba Starling grounded out to end the game.

Lindor hit his 22nd homer, a blast to right field off Jakob Junis (8-12) to give Cleveland a 4-0 lead.

Rookie Zach Plesac (7-4) allowed one run in 5 2/3 innings.

PIRATES 3, REDS 2

PITTSBURGH (AP) — Pablo Reyes hit a game-ending RBI single, driving in pinch-runner Joe Musgrove, and Pittsburgh rallied to beat Cincinnati.

Pittsburgh won for just the ninth time in 39 games since the All-Star break by chipping away at Reds closer Raisel Iglesias (2-9).

The Pirates put together three straight singles to start the ninth, the last a flare to shallow center by Adam Frazier that scored pinch-runner Erik Gonzalez. A sacrifice bunt by Jacob Stallings moved Musgrove to third and Reyes sent a drive to the gap in left-center to give Pittsburgh its eighth straight home victory over the Reds.

Felipe Vázquez (4-1) picked up the win by pitching a scoreless top of the ninth.

RAYS 7, ORIOLES 1

BALTIMORE (AP) — Austin Meadows hit his first career grand slam to cap a seven-run second inning, Trevor Richards shined in his second start with Tampa Bay and the Rays beat Baltimore.

Meadows hit a 2-0 pitch from Ty Blach (0-2) deep into the center-field seats to send Tampa Bay to its fourth straight win over Baltimore.

Tampa Bay has won 11 of its last 12 away games and now sits atop the AL wild-card standings. The Rays’ 42-23 road record is the best in the majors.

Richards (1-0) allowed Baltimore two hits and a walk over six shutout innings.